©2006-07 Acquisita LLP. All rights reserved. www.acquisita.com Client: Support Services Business Project Owner: Managing Director Role and objective We acted as a consultant to review a maintenance business as a potential acquisitions target.
Mucosal Morbidity in Patients With Epidermolysis Bullosa Acquisita Markham C. Luke, MD, PhD; Thomas N. Darling, MD, PhD; Roger Hsu, MD; Ronald M. Summers, MD, PhD;
Epıdermolysıs Bullosa Acquısıta Epidermolysis bullosa acquisita (EBA) is an acquired chronic subepidermal blistering disease that occurs primarily in adults, though an increasing number of childhood EBA has been reported over the last few years.
sis bullosa acquisita (EBA), 3 or pemphi gusvulgaris. 4 Wereportfindingsinapatientwhowas referredwithCCCassociatedwithamu cocutaneousautoimmunediseasethatwas
EPIDEMIOLOGIA • Incidenza CAP: 3-5 casi/1000 persone • Negli USA: 4 milioni di persone/anno • Mortalità: 5-15% nei pazienti ospedalizzati • Attivitàdi PS: 75-80% dei pz con CAP viene valutato in PS e ~ ¼viene ricoverato • Il costo di una degenza è25 volte maggiore di quello della ...
54 PDQ ORAL DISEASE Vesiculobullous Diseases Epidermolysis Bullosa Etiology •A diverse group of predominantly cutaneous, but also mucosal, mechanobullous diseases •Inherited form: autosomal dominant or recessive patterns may occur •Acquired form (acquisita): autoimmune from autoantibodies ...
Dermal binding may also be present in pemphigoid, demonstrating a combined pattern with both epidermal and dermal localization.*In*epidermolysis*bullosa*acquisita,*blistering*also* occurs in a subepidermal location, and IgG antibodies also bind to basement membrane zone components.
A heterogeneous group of patients, including 51 patients with pemphigus vulgaris, one with pemphigus vegetans, nine with pemphigus foliaceus, fi ve with paraneoplastic pemphigus, four with epidermolysis bullosa acquisita, and one with both bullous pemphigoid and graft vs host disease was included in ...
• Eosinophil involvement is usually greater in pemphigoid and epidermolysis bullosa acquisita • Serum IgA basement membrane zone (BMZ) antibodies bind to the epidermal, dermal or combined
bullosa acquisita, linear IgA disease, or dermatitis herpetiformis) Histology Perilesional skin biopsy Cutaneous Direct Immunofluorescence, Biopsy Serology Pemphigus Panel – IgG Epithelial Cell Surface Antibodies and Levels of IgG