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2 THE CAUSES OF ADDISON'S AND RELATED AUTOIMMUNE DISEASES immune system starts attacking the body's own organs. Autoimmune adrenalitis now accounts for around 70% of all cases, and affects more women than men.

Adrenal insufficiency

Chronic primary adrenal insufficiency has a prevalence of 93-140 per million and an incidence of 4·7-6·2 per million in white populations. 1-4 These recent numbers are higher than those reported during the 1960s and 1970s, 5,6 despite a continuous decline in tuberculous adrenalitis in the developed world ...

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C IGNA M EDICAL C OVERAGE P OLICY The following Coverage Policy applies to all health benefit plans administered by CIGNA Companies including plans formerly administered by Great-West Healthcare, which is now a part of CIGNA.

SYMPTOMS - Hyperthyroidism - WhAT IS ThE ThYr OID GlAND?

Hyperthyroidism This page and its contents are Copyright © 2012 the American Thyroid Association SYMPTOMS What are the symptoms of hyperthyroidism?

Adrenal Insufficiency

© Specialty Laboratories 2001 Adrenal Insuff 10/09/01 TN 1093 Adrenal Insufficiency Overview The majority of cases of chronic primary adrenal insufficiency (Addison disease) in the U.S. are caused by autoimmune adrenalitis.

Adrenal 2007 for website

•Isolated Autoimmune Addison Disease Pathologic Changes in Autoimmune Adrenalitis •Gross: –Very small glands (1 - 1.5 grams) –Cortices markedly thinned

Chapter 5. Pathophysiologyof endocrinesystem (L.Zlatoˇs) - 5 ...

adrenalitis,theadrenalisthesoletargetoftheau toimmunereaction(isolatedautoimmuneadrenocor ticalinsufficiency),butintheremainder,otheren docrineglandsareconcomitantlyaffected.

Predisposing Factors for Adrenal Insufficiency

In addition, certain forms of autoimmune adrenalitis have hereditary components, either with an autosomal recessive pattern of inheritance (autoimmune polyglandu-lar syndrome 1) or with an autosomal dominant pattern involving incomplete penetrance (autoimmune polyglandular syndrome 2).

101796 Adrenal Insufficiency

CURRENT CONCEPTS Volume 335 Number 16 * 1211 In patients with primary adrenal insufficiency caused by autoimmune adrenalitis or adrenomyelo-neuropathy, imaging of the adrenal glands is not necessary.


autoimmune adrenalitis has been documented as the commonest cause of primary adrenal insufficiency, 1, 9 this case is due to tuberculous adrenalitis.