free fraction of lidocaine in the presence of bupiv- acaine at clinical concentrations in vitro, which sug- gests that the combined administration of these drugs
dose infusion used was therefore 12.5 mg/h of bupiv- acaine and 20 pg/h of fentanyl. Patients receiving these infusions received no other anesthetics or anal-
Local anesthetics as antimicrobial agents - Combined silver sulfadiazine and bupivacaine in wound treatment-Antimicrobial activity of local anaesthetics used for dental analgesia - - Ropivacaine poor antimicrobial effect - Bactericidal activity of 0.5% bupivacaine with preservatives on ...
Bupiv vs. levo vs. ropiv Ñ Camorcia Ñ MLAD / ED50 study Ñ potency: bupiv > levo > ropiv Ñ Van de Velde Ñ full dose response study (ED 95 + ED 50) Ñ potency: bupiv > levo & ropiv
... 4 0.5-2 Alfentanil 10 1-2 0.25 0.25-0.5 Fentanyl 100 5-10 0.5-1 25-100 µg Sufentanil 750 3-5 0.5-1 10-30 µg Remifent 250 1-2 0.2 Stadol 5 5-10 2-4 0.5-2 Toradol 9 (30mg) 30-60 3-7 30-60 Lumbar Epidural Proced PFMS Pelvic 4 mg Abdom 6 mg Thoracic 8 mg Epidural Infusion PFMS 20 mg + Bupiv 200 mg in 200 ml NS Fentanyl 2 mg + Bupiv ...
--example formulaeexample formulae Morphine 50 mcg/mL + Bupiv. 1.0 mg/mLMorphine 50 mcg/mL + Bupiv. 1.0 mg/mL Hydromorphone 20 mcg/mL + Clonidine 1 mcg/mL Hydromorphone 20 mcg/mL + Clonidine 1 mcg/mL
-Differed from other studies where interscalene was consistently superior for the primary end point of analgesia.-Used 20 ml 0.2% bupiv.-Did not fully exploit intra-op benefits. ©2008 The University of Iowa Department of Anesthesia
Meds Used: NTG Lido Lido + Bupiv Bupiv + Other Meds Prescribed: NTG NTG+ Diltiazam Lido Lido/Prilo Hydrocort Lotrisone Miralax Nifedipine Nifedipine+
The stability of S-bupiv-acaine to chiral inversion in vivo is also consistent with previous studies (4). The AUC and C max of S-bupivacaine were somewhat higher than the sum of the values for Rand S-bupivacaine after administration of rac-bupivacaine consistent with the slightly higher dose employed.
Safe Practice and Toxicity • SIDE EFFECTS of LA • Toxicity - Vasovagal - Allergy - Nerve Trauma • Toxicity - largely related to blood levels • usu. follow appropriate dose iv OR excessive dose • circumoral .numbness, tinnitus, lightheadedness • convulsions • cardiac depression to arrest (Bupiv.