Vitamin B 1 Status Assessed by Direct Measurement of Thiamin Pyrophosphate in Erythrocytes or Whole Blood by HPLC: Comparison with Erythrocyte Transketolase
A New Approach to Erythrocyte Transketolase Measurement ' L. G. WARNOCK Department of Biochemistry, Vanderbilt University, and the Research Division, Veterans Administration Hospital,
261 TuE AuEaIcAN JOURNAL OP CLINICAL NuTRITIoN Vol. 23, No. 3, March, 1970, pp. 261-266 Printed in U.S.A. Original Communications Erythrocyte Transketolase Activity
The Determination of Thiamin Pyrophosphate in Blood and Other Tissues, and Its Correlation with Erythrocyte Transketolase Activity1 L. G. WARNOCK, C. R. PRUDHOMME
Plasma thiamin pyrophosphate and erythrocyte transketolase in chronic alcoholism1-3 Donald S. McLaren, M.D., Ph.D., M. R. C. P.E., Martin A. Docherty, B. Sc., and
304 ABBREVIATIONS: TTFD Thiamine tetrahydrofurfuryl disulfi de TKA Erythrocyte transketolase TPPE Thiamine pyrophosphate effect on TKA ATEC Autism Treatment Evaluation Checklist Delta ATEC Final ATEC score subtracted from baseline ATEC Introduction The hypothesis that TTFD might have a benefi ...
The mean packed cell volume, serum albumin, and erythrocyte transketolase activity were normal, indicating that they werelikely to have been adequately nourished.
Thiamine, riboflavin, and vitamin B-6 activity coefficients of erythrocyte transketolase (EC 126.96.36.199), erythrocyte glutathione reductase (EC 188.8.131.52), and erythrocyte *-aspartic aminotransferase (EC 184.108.40.206) were used as functional indexes for the status of the 3 vitamins, respectively.
Twenty adolescent patients with abnormal erythrocyte transketolase were treated successfully by nutritional correction (Lonsdale, D., Shamberger, R. J.,1980), suggesting that our 17 patients may represent these adolescents in their later years.
A continuous-flow (Auth-Analyzer ID procedure for measuring erythrocyte tranaketolass activity. Cliii Chem 1982;28:2206-13. 22. Warnock LG. TransketoLase activity of blood hemolysate, a useful index for diagnosing thiamin deficiency.