INTRODUCTION Bone resorption is necessary for many skeletal processes. It is an obligatory event during bone growth, tooth eruption and fracture healing, and is also necessary for the maintenance of an appropriate level of blood calcium.
Perspectives on Osteoblast and Osteoclast Function 1 C. V. Gay,*, †,2 V. R. Gilman,†and T. Sugiyama‡ *Department of Poultry Science, The Pennsylvania State University, 213 William L. Henning Building, University Park, Pennsylvania 16802-3501; †Department of Biochemistry and Molecular ...
BIOLOGY OF NEOPLASIA Biology of Osteoclast Activation in Cancer By G. David Roodman Abstract: Bone is a frequent site of cancer metastasis. Bone metastases can result in bone destruction or
98 Current Rheumatology Reviews , 2009, 5, 98-110 1573-3971/09 $55.00+.00 © 2009 Bentham Science Publishers Ltd. Osteoclast Apoptosis in Rheumatic Diseases Characterized by a High Level of Bone Resorption (Osteoporosis, Rheumatoid Arthritis, Myeloma and Paget's Disease of Bone) Sophie Roux *,1 ...
Primary Human Osteoclast Differentiation and Function on Dentine Discs and Corning ® Osteo Assay Surface A. Fawad Faruqiand James Beltzer Corning Incorporated Sullivan Park, NY 14831 Introduction In vitro assays that can measure both the formation and function of os teo c lasts are critic al ...
Arthritis Research & Therapy Vol 9 No 1 Andersson et al. Page 2 of 14 (page number not for citation purposes) Introduction Aseptic loosening of a joint prosthesis is associated with remodelling of bone tissue in the vicinity of the prosthesis.
Stimulation by Toll-Like Receptors Inhibits Osteoclast Differentiation 1 Masamichi Takami, 2 Nacksung Kim, 2 Jaerang Rho, and Yongwon Choi 3 Osteoclasts, the cells capable of resorbing bone, are derived from hemopoietic precursor cells of monocyte-macrophage lineage.
Gender- and age-related differences in osteoclast formation from circulating precursors M Jevon, A Sabokbar, Y Fujikawa, T Hirayama, S D Neale,
327 J Musculoskel Neuron Interact 2001; 1(4):327-332 Perspective Article Osteocyte-osteoclast morphological relationships and the putative role of osteocytes in bone remodeling C. Palumbo, M. Ferretti, A. Ardizzoni, D. Zaffe, G. Marotti Department of Morphological Sciences and Legal Medicine ...
Osteoclast Ontogeny Macrophage Osteoblast Monocyte Myeloid cell RANKL M-CFS RANK c-fms Polarized osteoclast Osteoclast Haematopoietic precursors Pre-osteoclast