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Screening for Down Syndrome

Abstracts from previous meetings indicated that the sensitivity of screening for Down syndrome was nearly 90% with a 5% false-positive rate, which is similar to the results of the SURUSS trial.

First and second trimester antenatal screening for Down's ...

First and second trimester antenatal screening for Down's syndrome: the results of the Serum, Urine and Ultrasound Screening Study (SURUSS). Health Technol Assess 2003; 7 (11).

Clinical Review Criteria: First trimester detection of Downs ...

Medical Technology Assessment Committee (MTAC) Date Evidence Conclusion Outcome 4/4/05 Findings of the Serum, Urine and Ultrasound Screening Study (SURUSS) suggest that the optimal screening method is an integrated test including first and second trimester maternal serum markers and fetal NT measurements.

Antenatal Screening for Down's Syndrome

First and second trimester antenatal screening for Down's syndrome: the results of the Serum, Urine and Ultrasound Screening Study (SURUSS) Antenatal Screening for Down's Syndrome

NT Providers Progress Report 4

SURUSS report page 20 supports SAMSAS observation of NT only performance at a 5%RR (where they state a DR 63%, 95%CI 51 to 75%). • SURUSS report page 40 states NT "has poor performance as a screening test for Down's syndrome on its own or with maternal age alone."

Nuchal translucency and gestational age

remodelled the already modelled SURUSS data (Wald et al., 2003a) to claim, firstly, that their results are now similar to thoseofthemulticentre study co-ordinatedby

CIGNA's medical coverage position on Down syndrome screening

The Serum Urine and Ultrasound Screening Study (SURUSS) was a multi-center, prospective clinical trial of over 47,000 subjects, conducted in the United Kingdom and Austria.

INTEGRATED SCREENING

First and second trimester antenatal screening for Down's syndrome: The results of the Serum, Urine, and Ultrasound Screening Study (SURUSS). Journal of Medical Screening . 2003;10:56-104.

First-Trimester Detection of Down Syndrome Using Fetal ...

The Serum, Urine, and Ultrasound Screening Study (SURUSS) study enrolled over 47,000 women, 101 of whom had fetuses with Down syndrome. (3) This study evaluated several tests in parallel, including first-trimester testing with NT and maternal markers, the triple test, second-semester quadruple test ...

New choices in prenatal screening for Down syndrome

Also discussed are the findings of recent studies, including 2 key trials: •the First and Second Trimester Evaluation of Risk (FASTER) of aneuploidy trial, published in November 1 •the Serum, Urine, and Ultrasound Screening Study (SURUSS), published in 2003 in the United Kingdom 2 These 2 trials are ...