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Telomerase

Developmental Control of Telomere Lengths and Telomerase ...

The Plant Cell, Vol. 10, 1691–1698, October 1998, www.plantcell.org © 1998 American Society of Plant Physiologists Developmental Control of Telomere Lengths and Telomerase

TELOMERASE ACTIVITY AND TELOMERE LENGTHS IN HUMAN FIBROBLAST ...

ABSTRACT Telomerase is an enzyme that helps maintain the telomeric ends of chromosomes during DNA replication. Telomere lengths represent a balance between telomerase activity attempting to elongate their ends, and cell division that causes telomere shortening.

Telomerase PCR ELISA

CONTENTS 7 BIOCHEMICA ■ NO. 4 [1996] NEW PRODUCTS Telomerase PCR ELISA For fast and sensitive detection of telomerase activity Boehringer Mannheim's Telomerase PCR ELISA is designed for the highly sensitive qualitative detection of telo-merase activity in cell extracts from cell cultures and ...

Telomerase in germ cells

Introduction Telomerase is a ribonucleoprotein that adds hexameric repeats to the mammalian telomeres to compensate for the loss of basepairs that occurs after subsequent rounds of DNA replication.

Telomeres, telomerase, and cancer: life on the edge of ...

74 Telomeres, telomerase, and cancer: life on the edge of genomic stability Rena Oulton, BSc , and Lea Harrington, PhD The presence of telomerase activity in most human tumors, but not in many normal somatic tissues, has raised considerable interest in telomerase as a possible anticancer therapy.

Comparative Expression of Human Telomerase Catalytic Subunit ...

1 Comparative Expression of Human Telomerase Catalytic Subunit in Normal and Tumor Breast Cell Lines Denise Collado Biology Department, Fordham University, Bronx, NY 10458 dcollado@fordham.edu Abstract Telomerase is a ribonucleoprotein responsible for maintaining the length of telomeres by ...

Increased telomerase activity and comprehensive lifestyle ...

Articles 1048 www.thelancet.com/oncology Vol 9 November 2008 Increased telomerase activity and comprehensive lifestyle changes: a pilot study Dean Ornish, Jue Lin*, Jennifer Daubenmier*, Gerdi Weidner, Elissa Epel, Colleen Kemp, Mark Jesus M Magbanua, Ruth Marlin, Loren Yglecias, Peter R Carroll ...

Inhibiting Telomerase Activity in hTERT-immortalized RPE ...

Inhibiting in vitro Telomerase Activity 3 Abstract hTERT over-expressed retinal pigment epithelial (RPE) cell cultures were transfected with a complementary, sequence-specific 8-mer 2‟-O-methyl RNA oligonucleotide and assayed after a 20 hour period for telomerase activity with the standard ...

Commentary Methods Used in Evaluating Telomerase Activity

Recent studies have shown that the progression of neoplastic lesions is characterised by the reactivation of telomerase, a ribonucleoprotein complex which stabilizes telomere length by adding hexameric repeat (TTAGGG)n to telomeric ends of human chromosomes (1).

Telomerase Detection Kit Manual

Table of Contents 1. Introduction Background Product Overview Quantitative Telomerase Detection Kit Description Quantitative Telomerase Detection Kit Contents Storage and Stability Warnings and Precautions 2.